Anonymous
Anonymous asked in 社會與文化語言 · 1 decade ago

醫學期刊幫我翻譯一下!!拜託拜託

The main reason to pursue this next ambitious venture in large-scale biology with great urgency is cancer's terrible toll on humankind. Every day more than 1,500 Americans die from cancer--about one person every minute. As the U.S. population ages, this rate is expected to rise significantly in the years ahead unless investigators find ways to accelerate the identification of new vulnerabilities within cancerous cells and develop novel strategies for attacking those targets.

Still, however noble the intent, it takes more than a desire to ease human suffering to justify a research enterprise of this magnitude. When applied to the 50 most common types of cancer, this effort could ultimately prove to be the equivalent of more than 10,000 Human Genome Projects in terms of the sheer volume of DNA to be sequenced. The dream must therefore be matched with an ambitious but realistic assessment of the emerging scientific opportunities for waging a smarter war against cancer.

A Disease of Genes

THE IDEA THAT ALTERATIONS to the cellular genome lie at the heart of all forms of cancer is not new. Since the first identification in 1981 of a cancer-promoting version of a human gene, known as an oncogene, scientists have increasingly come to understand that cancer is caused primarily by mutations in specific genes. The damage can be incurred through exposure to toxins or radiation, by faulty DNA repair processes or by errors that occur when DNA is copied prior to cell division. In relatively rare cases, a cancer-predisposing mutation is carried within a gene variant inherited from one's ancestors.

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  • 1 decade ago
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    最主要的原因,要實現這個雄心勃勃的未來創業大型生物學與具有相當的緊迫,是癌症的可怕的損失,對人類的生活。每天有1500多名美國人死於癌症-關於一人,每一分鐘。隨著美國人口的老齡化,這個比率可望大幅上升,在未來數年內,除非調查人員找到辦法,以加速確定新的安全漏洞與細胞的癌變和發展新型戰略攻擊這些目標。

    但是,不論如何崇高的意圖,它需要一個多慾望,以減輕人類的痛苦,以證明一個研究企業的這種規模。當應用到50種最常見癌症,這一努力最終可能被證明是相當於超過10000人類基因組計劃的條款規定數量的DNA被測序。夢想,因此必須配合一個雄心勃勃,但現實地評估新興的科學機遇,為發動戰爭聰明反癌症。

    一種疾病的基因

    主張改建,以適應細胞基因組的核心所在,所有形式的癌症並不新鮮。自從第一次鑑定,在1981年的一個毒瘤促版本的人類基因被稱為癌基因,科學家們越來越認識到癌症是造成的,主要由基因突變的特殊基因。該損害可招致通過接觸毒素或輻射,是由錯誤的DNA損傷修復過程或錯誤發生時, DNA是複製之前細胞分裂。在較為罕見的情況下,癌症的誘發突變是進行內部的一個基因變異繼承自一個人的祖先。

    Source(s): 我的翻譯工具
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