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what is acetylcholine?

can you please explain to me and give me an example from using these notes?


a. Acetyl CoA + choline

b. mostly excitatory, sometimes inhibitory

c. broken down by acetycholinesterase enzyme in cleft and postsynaptic membranes

4 Answers

  • 1 decade ago
    Favorite Answer


    a. Acetyl CoA + choline

    <acetyl + coenzyme A+ choline- acetylcholine>

    b. mostly excitatory, sometimes inhibitory

    <this hormone is a trigger for causing neuro impulses aka Action Potentials. It may excite (causea) the action potential at or above threshold(level needed for an axon impulse) OR inhibit the action potential causing no impulse or a Graded potential.>

    c. broken down by acetycholinesterase enzyme in cleft and post synaptic membrane

    <it is broken down by acetycholinesterase in the post synaptic cleft and postsynaptic membrane>

    hope that helps..

  • 1 decade ago

    acetylcholine is a chemical compound found in the body that acts as a neurotransmitter. your first note is about the compounds that make up acetylcholine: acetyl coenzyme A and choline. the enzyme choline acetyltransferase takes these two compounds and creates acetylcholine. once created, it acts as a neurotransmitter in the brain and in the peripheral nervous system. this means that it acts to relay signals between the synaptic cleft in neurons. what your note b means is that sometimes acetylcholine is used as an excitatory neurotransmitter, in that it proliferates the signal. so if a signal is being sent in the brain, acetylcholine will keep the signal going. it's only rarely inhibitory, meaning that it will help to slow down and stop the signal. your final note indicates that once acetylcholine is released from the axon and its signal has been sent, what happens to it? it just sits in the cleft until the it is broken down. actually, i'm fairly certain that the enzyme that does this is cholinesterase, breaking it down into choline and acetic acid. acetylcholinesterase inhibitor stops this from happening, inhibiting the enzyme

  • 1 decade ago

    achetylcholine is a neurotransmitter that sends out signals to contract/expand muscle cells. its made up of acetyl coa and choline.


    1. action potential opens volt-gated Ca2+ that is attached to the muscle

    2.Ca2+ starts teh release of ACh from the synaptic vesicles.

    3. ACh is released in the synaptic cleft.

    Ach diffueses and binds to ligand-gated Na+. (this is where it will open the Na+ gate; so it excites/inhibits here).

    Actehycholinesterase enzyme breaks down the ACh after its been used. if it doesnt break it down, the body builds up too much and spasams and such happen.

    actehycholinesterase breaks the ACh apart. the choline goes up the cleft, the Acetyl Coa goes back into the synaptic vesicles and is used again. Choline is created from metabolism, so then the left over Acetyl CoA gets reused.

    there are more steps, but just going from your notes.

  • 1 decade ago

    A white crystalline derivative of choline, C7H17NO3, that is released at the ends of nerve fibers in the somatic and parasympathetic nervous systems and is involved in the transmission of nerve impulses in the body.

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