I just started taking this about 6 weeks ago.
About an hour after I took my very first pill, I felt incredibly better. It was amazing! I lost my appetite and had slight nausea, but I've also lost 10 lbs - so I'm not complaining!
The first couple of days I was bright-eyed and bushy tailed, I didn't sleep for 72 hours straight. For a few weeks I had to take Benadryl to knock me out at night. That's all corrected itself and I'm sleeping better now.
I've started clenching my teeth oddly enough, and that's caused some headaches but I'm getting one of those bite blockers to help with that.
I have night sweats, although I'm not sure if that's from the Cymbalta. I also have a thyroid condition - and my levels are high, so I have to adjust my dose and see if that helps, which it should. My doc did say the night sweats could be caused by Cymbalta, but it's highly unlikely given my thyroid levels.
Honestly, I've never felt better in my life. I was tired all the time before, needless to say, I was never motivated to do much exercise. Since then I've started jogging and dieting. I used to be a fast food junkie, a serious crap-atarian. If you shouldn't eat it, chances are, I was craving it. Now, none of that even tastes good to me. I can process my thoughts and emotions a million times better than I could before. I used to feel like a complete basket case, but now I can put things into perspective. I'm not constantly crying over stupid things. I can communicate effectively now - where before I'd tend to fly off the handle. My boyfriend used to tell me he thought I was crazy at times (and I felt that way too). We haven't fought once since I've started taking Cymbalta. It's hard to explain, but if I was upset about something before, it would usually snowball and start to feel like this huge thing. Now I'm able to process the fact that I'm upset, but it's not that important to me anymore. It's like my perspective has changed.
The only downfall to Cymbalta that I can see is the fact that I don't see as many emotional highs as I did before. I miss that feeling, but honestly I can't complain given the complete 180 I've done in such a short period of time. I am in love with this drug, I don't know how I ever lived without it.
Oh yeah, you asked about memory loss. The first couple weeks I felt a little forgetful, but I'm the type who writes everything down at work anyway - so it wasn't an issue, I had notes.
On occasion I feel slightly dizzy when standing. It's not like the typical dizziness, but more like a feeling that I'm in one of those old motion pictures where the pictures are spliced together to make the movie - so there's this lack of flow. It's hard to explain - it's not really bothersome or anything (and doesn't happen often), it's just odd.
Oh, and most people REALLY want to know about the effects in the bedroom department. If I'm 'alone', it takes much longer to get the job done. I haven't noticed any issues when I'm with my bf, I don't know if that's just because he's mad good at what he does or what.
Anyway, enough babbling - I just thought since I've recently started taking it, you might be interested in hearing my experience.
I love, love, love it!