My usb was not detected by my computer or another computer,there is no flashing light and no detction message?

my usb flash drive was not detected by my computer and there is no flashing light when i inserted it to the usb port. What seems to be the problem? Are there any solutions for my problem?...thanks..
Update: I used my flash drive one time and it was still well.. the second time i used it the computer can no longer detect it even if i use another computer just to make sure that it can be detected but unfortunately still there was no detection. What seems to be the problem?? pls. help..
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