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Who was the first to identify the chemical differences between DNA and RNA?

I'm looking for the name of a geneticist or a scientist. I've narrowed it down to 4: Levene, Garrod, Franklin & Griffith.

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  • Anonymous
    1 decade ago
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    In 1919 Phoebus Levene's identified the base, sugar and phosphate nucleotide unit. Levene suggested that DNA consisted of a string of nucleotide units linked together through the phosphate groups. However, Levene thought the chain was short and the bases repeated in a fixed order.

    Nucleic acids were discovered in 1868 by Johann Friedrich Miescher , who called the material 'nuclein' since it was found in the nucleus. It was later discovered that prokaryotic cells, which do not have a nucleus, also contain nucleic acids. The role of RNA in protein synthesis had been suspected since 1939, based on experiments carried out by Torbjörn Caspersson, Jean Brachet and Jack Schultz. Hubert Chantrenne elucidated the messenger role played by RNA in the synthesis of proteins in ribosome. Finally,Severo Ochoa discovered the RNA, winning Ochoa the 1959 Nobel Prize for Medicine. The sequence of the 77 nucleotides of a yeast RNA was found by Robert W. Holley in 1964, winning Holley the 1968 Nobel Prize for Medicine. In 1976, Walter Fiers and his team at the University of Ghent determined the complete nucleotide sequence of bacteriophage MS2-RNA.

    Source(s): wiki yo
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