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睿嫻
Lv 7
睿嫻 asked in 健康其他:保健 · 1 decade ago

請問avandamet是糖尿病用藥嗎

請問avandamet是糖尿病用藥嗎

可以順便告訴我其商品名或是學名嗎

作用機轉也請一起給我

謝謝

1 Answer

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  • 1 decade ago
    Favorite Answer

    Avandamet (梵帝美錠)--目前市面上有3種規格(500mg/1mg, 500mg/2mg, 500mg/4mg)

    ----成份 : Metformin HCL + Rosiglitazone maleate

    ----臨床用途: 第二型糖尿病。

    ----作用機轉 :

    Rosiglitazone主要針對第二型糖尿病的潛在誘因,直接作用在胰島素耐藥性(Improved insulin sensitivity in adipose & muscle tissue, reducing insulin resistance)。metformin 作用主要於降低肝臟生產葡萄糖的量(Reduction in hepatic glucose production, reduction in intestinal glucose absorption, increased insulin sensitivity),兩种藥物合併使用時,能靶向作用於核心的代謝缺陷機制,從而獲得療效更好的臨床益處。

    ----用法與用量

    依據個人用藥的效果及耐受度來決定,同時以不超過每日最大建議劑量8mg(rosiglitazone)/2000mg(metformin) 為限。

    ----禁忌

    已知對 rosiglitazone、metformin 或任何賦形劑過敏。糖尿病酮酸酸血症或昏迷。腎衰竭(例如:男性血清肌肢酸濃度 > 135 < μ > mol/L 或女性 > 110 < μ > mol/L)。

    Source(s): 藥品仿單 + 專業知識
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