There are 2 from secrets of a successful marrage that I find very funny.
1. At the start Homer, Moe etc are playing poker.
D'oh! D'oh! D'oh! Uh, I mean, woohoo.
I'm in. Let's see your cards.
Oh, I was bluffing.
Ha-ha-ha-ha-ha! Come to papa! I... wait a minute. Homer, you have a straight flush! Oh, you do this every time, you... oh god, I'm choking on my own rage here!
Hey, don't yell at Homer, just because he's a little slow.
(Homer gasps. The shot then pans up to his brain.)
Something was said, not good. What was it? Don't yell at Homer? Nah, that's okay. What was it... slow! They called you slow!
(standing up and pointing) How dare you call me that! I--
(We see that it is now night-time. Lenny is in his dressing gown, raiding the fridge.)
Hey Homer, are you still here? Boy, you are slow.
(Homer gasps. His brain speaks again.)
Something said, not good.
Get the Hell out of here!
(He kicks Homer out.)
2. Later in the same episode Homer goes to teach at the local college adult education annex. Moe also has a class there Funk dancing for self defence.
All right, here's the four-one-one, folks. Say some gangster is dissing your fly-girl. You just give him one of these.
(He plays some funk music and dances. Suddenly, he pulls out a shotgun and shoots into the air.)
Ooh! Ah! Ooh!