You have done a good job of providing information - far better than most questions on this site - but we cant see the scans or examine what must be palpable lymphadenopathy and there still is a great deal of missing information. What was the size of the primary breast mass? Can it still be palpated and measured? CT scans of chest and abdomen looking for lung and /or liver involvement? Bone Scan? Serum tumor markers? Serum chemistries. etc. Why would you want to use useless, unscientific, unproven homeopathic treatments? Some supplements can interfere with the effectiveness of the expensive chemotherapy drugs she is receiving. Of the three different combination chemotherapy treatments she has had so far, I like the Cyclophosphamide, 5FU, and Adriamycin best - but that is just my preference. There are many variations - many chemo drugs and regimens that have been used effectively for breast carcinomas. There is still Taxol or Herceptin to try. What has been the clinical response to the three treatments of chemotherapy already given? Have there been repeat scans or physical examination evidence of response? Many of those lymph nodes described on the PET scan must be easily palpable and measurable. Still so much missing information here. The doses seem OK. Why use tamoxifen when the primary carcinoma has negative hormonal receptors? But we should not be second guessing the medical oncologist who has all of the information and has seen this person. You should have the option of a real second opinion - not an internet query - if you are not happy with the care. "IF" this is truly "stage IV" breast carcinoma, the goal is not a cure. The goal is to gain as much quality survival time as possible. Stage IV metastatic breast carcinoma is not considered a curable malignancy - though some patients can do well for years. The oncologist should have explained this in detail. Even though ~six months were wasted on useless homeopathic treatment, this disease had likely spread already back in March when the primary breast mass was found, so the delay before appropriate scientific treatment has probably not been a difference maker here. We believe that most breast cancers have been growing for years before they are clinically detectable, so you need not have too many regrets about that 5-6 month delay. I would not suggest any homeopathic supplements while you are trying chemotherapy, but it would be a good idea to ask your oncologist what he thinks about this. We all have our own opinions. At the university medical centers where I received the 13 years of training to be a board certified cancer chemotherapy specialist, none of the professors or attending physicians thought highly of homeopathic remedies.