One of the long term complications of diabetes mellitus (both types) is nerve damage. It's not clear, even now, just why. It may be the high levels of glucose (it's slightly toxic, because it's chemically reactive), or it may be due to another derangement of one of the many body systems insulin controls or affects. And diabetics' insulin levels are usually out of whack (none for type 1) and even too much (in type 2, but with some of its important effects (controlling glucose absorption by about 2/3 of body cells). However it happens, the damage is often seen first in sensory nerves in the feet and lower legs and later, sometimes, in hands, fingers, and such. Nobody feels very well with their feet anyway (imagine wearing hot sweaty shoes on your sensitive hands!) and the loss in sensation is sometimes just missed. And you miss blisters, punctures, infections, ... until they get out of hand. Something that's not well understood at all is the pain "in' the feet and lower legs that sometimes occurs. If the sensory nerves are dead or out of commission, how could there be pain? It appears to be related to the problem of phantom pain in some folks who have lost limbs. the missing limb still has parts of the brain watching it, and something in the missingness of the part that's isn't there anymore, but still being watched causes the brain to decide tat the signals it isn't getting really, are from ice picks stabbing into the missing foot or some really painful such thing. Clearly, no treatment of the damage to the missing foot is going to relieve the pain. And the usual pain killers don't always work very well, as the pain seems to be happening in parts of the brain the pain killers often don't help. For diabetics, even if they haven't lost anything to infection or circulation damage, the feet and lower legs might as well not be there (the sensory nerves aren't reporting in like they should), and it may be that the brain parts listening to those parts may be getting just as out of whack as if the part were actually missing. No news, after all. There are some non-traditional pain killers which have worked for some people. One mentioned to me not long ago is something called Neurontin. It might help. The pain can be quite intense, even debilitating. If so, it may make sense to consult a doctor who's a specialist in pain management. But before that, make sure you've talked to a doctor with more the general expertise in diabetes. It's a complex situation in many people and the long term complications make it more complex still. since this appears to be a nerve damage problem, I'd suggest you might try a neurologist, or failing that, an endocrinologist. Both are likely to be better informed about odd diabetic nerve issues than the usual family practitioner. If nothing helps, try a pain specialist -- they're not very common and will be harder to find than neurologists or endocrinologists. A last possibility is a clinic at a teaching hospital, if there's one near you. The doctors in training need practice, and they're supervised by some of the sharpest docs and profs available, and they're expected to consult on difficult cases. And the clinics tend to be less expensive than hospitals, though more expensive than an office visit with a family practice doc. Best wishes for her. people who haven't experienced what this can be (horrid!) usually just don't get it. Walk it off is probably what the local athletic coach or trainer might say, or wait it out from some tough guy, or rub this cream on from a concerned nurse. None of these are likely to make much difference.