can anyone describe the actions of B cells and t cells in an immune response?

3 Answers

  • Mary
    Lv 4
    1 decade ago
    Best Answer

    I agree with the previous poster. T-cells are the ones that grab onto the antigens in your body (bacteria, viruses, etc). The T-cells then present them to the B-cells, which are the ones that actually make antibodies against the antigens. B-cells and their antibodies are called humoral immunity. T-cells and their effects on other cells are called cellular immunity.

    There is an "Infection and Immunity" tutorial in the link below. I recommend the "Cells of the Immune System" and "Humoral Immunity" sections for more information. You can also Google for "humoral immunity" and find some other sites.

  • Emmy
    Lv 6
    1 decade ago

    The simplified answer is that B cells produce antibodies to specific viruses and bacteria, while T cells are cytotoxic, and kill invading or mutated cells.

    B cells are part of the system known as humoral immunity, and T cells are involved with cell mediated immunity.

  • 4 years ago

    It's kind of a long process & kinda hard to explain without marcophages but here goes...Macrophages will ingest the bacterium and then present the microbes antigen on its cell surface as MHC II complexes so corresponding type 1 helper T-cells (TH1)/(CD4+ cells) can identify it so antibodies can eventually be produced via T-dependent clonal selection theory. The macrophage will also secrete interleukins (IL) known as IL-12 that will help activate other TH1 cells. These TH1 cells will begin to secrete cytokines known as interferon-gamma & IL-2 to assist in the process of activating other macrophages as well as to help activate B-cells to produce immunoglobins and the activation of memory cells. This process here is more involved in allergy responses but anways...B cells in the thymus can also endocytosize foreign antigens that haven't been processed yet as MHC II as well so type 2 helper T-cells (TH2) can secrete IL-4 to allow the activation of other TH2 cells so B-cells can secrete antibodies particularly IgE antibodies to opsonize the foreign antigens to enhance phagocytosis as well as bind to other immune cell surface receptors such as basophils to assist in the acute inflammatory response due to the release of histamines, release of prostatoglandins, IL's, & cytokines into the surrounding tissues causing effects such as vasodilation, spasms, runny nose, & dyspnea. The amount of the foreign antigen can also lead to hyperstimulation of TH2 cells which could lead to an excess production of IL-4 that causes a cytokine storm and causing a type 1 hypersensitivity reaction to occur where anaphylaxis can occur. This entire process eventually also produces memory T & B-cells. Upon production these immunity cells are already pre-registered with that antibody so if later exposures occurs with that same antigen from the allegen then it will bind to these immunity cells to activate the cells again without you experiencing any physical symptoms because of polyclonal response due to a greater number of memory cells. Hope this helps some!

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