Dont ask this here, you will get a lot of people stating ignorant opinions when they know NOTHING about it at all!
I would ask your doctor or pharmacist. It depends on what you are taking it for and how much you are drink.
My partner takes Zoloft and we have been repeatedly told by doctors and pharmacists that one or two drinks a week will not dramatically interfer with the Zoloft.
HOWEVER, it can amplify the effects of the alcohol significantly. Even if under the legal alcohol limit, it may not be safe for you to drive etc. If you injure or kill someone, YOU ARE 100% LIABLE!
Also be aware that alcohol can increase depression, anxiety etc.
It is all about responsibility. Chat to a doctor/pharmacist. It may depend on what condition you are taking it for. If they say it is OK, never drink more than 1-2 drinks per week.