大師
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大師 asked in 社會與文化語言 · 1 decade ago

急~麻煩一下翻譯達人(這是關於牙周病方面的)

Biologists are now investigating the possibility that many chronic

illmesses,once attributed to other causes,may in fact stem from infection.

Several striking examples have been demonstrated in the past two

decades:Stomach ulcers,long attributed to stress,spicy food and genes,

turn out to derive,almost always,from the bacterium Helicobacterpylori.

Cervical cancer,it is now known,can develop only in women who have

been infected by certain varieties of the human papillomavirus(HPV),

long considered innocuous.Yet critics of the bacterial-cause theory point

out that oral bacteria survive poorly in the bloodstream.They also mote

that proinflammatory chemicals demonstrably leak from the gums into

the bloodstream,adding to the body's inflammatory burden.In a test tube,

proinflammatory agents from one group of cells can spark a response in

another group.Injecting proinflammatories into animals also produces

such a response.Some argue that these chemicals alone can explain the

association of gum disease and systemic illness.

Here is how it might play out.Imagine that there is some small irritation in

the wall of the coronary artery,perhaps the result of chemicals absorbed

from cigarette smode or car exhaust.If the overall inflammatory burden

is low,then perhaps these sites will remain quiescent. If,however,

proinflammatory chemicals have leached from the periodontal pocket into

the bloodstream,it might heighten local inflammation in the artery,

beginning the process of atherosclerosis.

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  • 1 decade ago
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    生物學家們現在正在探討 "在剔除了其他造成慢性病的病因之後, 發現許多慢性病可能源自於細菌感染之可能性". 在過去的二十年間, 已有數個引人注目的例子: 例如, 胃潰瘍的發生長久以來一直被認為是因為壓力, 辣的食物和基因的關係, 但是現在發現絕大多數的胃潰瘍發生的原因是由於名叫幽門螺旋桿菌 (Helicobacter pylori) 的細菌. 人類乳突病毒(human papillomavirus, HPV)一直被認為是對人體無害的, 但是現在也已證明子宮頸癌的發生與特定的一種人類乳突病毒的感染有關. 然而, "疾病源於細菌學說"(bacterial-cause theory)的批評家們指出, 口腔裡的細菌到了血管內之後, 它們的存活機率是很小的. 批評家們更指出, 前發炎性(proinflammatory)的化學物質被證明會從牙齦滲透入血管, 增加了人體發炎反應的負荷. 在試管裡, 從一種細胞散發出的前發炎性物質可以觸發另一種細胞發生反應, 注射前發炎性物質到動物體內也會產生同樣的反應.

    一些學者爭辯說: 這些化學物質(前發炎性物質)本身就可以用來解釋牙周病和全身性疾病之間的關聯. 以下是這個理論的解釋: 請試著想像在冠狀動脈的壁上有一些小小的發炎, 這些發炎的現象可能是因為吸入了抽菸時釋放出的化學物質, 或是吸入了汽車廢氣. 如果全面的人體發炎反應的負荷很低的話, 也許這些小小的發炎會保持著靜止狀態. 但是, 如果前發炎性物質從牙周囊袋滲透到血管內, 很可能會使動脈內的局部性發炎增高, 開始了動脈硬化症的形成.

    Source(s): taiwanese canadian
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