I've been on Protonix for 3 years. Can a person build up a tolerance to it?

My acid reflux seems to be coming back. Last time I had the esohagal scope done was back in 2003 and they said I had mild esophagitis and GERD. I also thought I read where being on that for a long period of time you can become B12 deficient. Is that true because my gastrointerologist has never mentioned it to me.

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  • Anonymous
    1 decade ago
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    yes, people can built a tolorence to any type of drug. in fact, protonix should not be used beyond 16 weeks without taking a break. also, you should not use aspirin while on protonix, the aspirin will decrease that effects that protonix is suppose to do,

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