Anonymous
Anonymous asked in HealthDiseases & ConditionsDiabetes · 1 decade ago

diabetic neuropathy?

role of ssri in diabetic neuropathy

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  • Anonymous
    1 decade ago
    Favorite Answer

    Treatment of early manifestations of sensorimotor polyneuropathy involves improving glycemic control. Tight control of blood glucose can reverse the changes of diabetic neuropathy. Despite advances in the understanding of the metabolic causes of neuropathy, treatments aimed at interrupting these pathological processes have been limited by side effects and lack of efficacy. . The drugs- imipramine, amitriptyline, desipramine and nortriptyline- are effective at decreasing painful symptoms but suffer from multiple side effects that are dosage dependent. One notable side effect is cardiac toxicity, which can lead to fatal arrhythmias.

    SSRIs (Selective serotonin reuptake inhibitors) include fluoxetine, paroxetine, sertraline and citalopram. They are less effective in relieving pain, but are better tolerated. Side effects are rarely serious, and do not cause any permanent disabilities. They cause sedation and weight gain, which can worsen a diabetis's glycemic control.

    "The SSNRI Duloxetine (Cymbalta) is approved for Diabetic neuropathy."

    By targeting both Serotonin and Norepinephrine. It targets the painful symptomes of diabetic neuropathy, and also treats depression if it exists.

    Carbamazepine (Tegretol®) is effective but not necessarily safe for diabetic neuropathy. Its first metabolite, oxcarbazepine, is both safe and effective in other neuropathic disorders, but has not been studied in diabetic neuropathy.

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  • 4 years ago

    1

    Source(s): Reverse Diabetes Without Drugs : http://DiabetesCure.raiwi.com/?uApt
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  • 4 years ago

    2

    Source(s): #1 Diabetes Cure System : http://DiabetesGoFar.com/?PwwL
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  • Anonymous
    4 years ago

    Home Treatment For Neuropathy

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  • 1 decade ago

    SSRIs or Selective Serotonin Reuptake Inhibitors are a group of drugs mainly used in treating depression, but recent trials have indicated that they may be useful in treating diabetic neuropathy as well, due to their action on GABA receptors.

    Now... there are different drugs in this group -- the most widely known being fluoxetine or prozac, which appears effective only in diabetic neuropathy with co-existing depression.

    Paroxetine and fluvoxamine appear to have some efficacy in diabetic neuropathy. SSRIs were the 1st to be FDA approved in the treatment of diabetic neuropathy.

    In general, however, they are less efficacious than tricyclic antidepressants. The mainstay of treatment, however, remains at controlling the diabetes itself and of course, as the old adage goes -- PREVENTION is better than cure.

    K... now may I have my 10 points? :-)

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  • 1 decade ago

    SSRI means 'selective serotonin reuptake inhibitors' and is a class of medications used for treating diabetic neuropathy. Diabetic neuropathy means the damage to the nerves that can happen with diabetes. Here is a link about that:

    http://familydoctor.org/050.xml

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  • Anonymous
    6 years ago

    A PROVEN Cure for Neuropathy and Diabetic Nerve Pain.

    If you or a loved one suffer from neuropathy, you will need to watch the controversial video that will expose to you the secret to permanently and naturally curing neuropathy in as little as 7 days.

    The short presentation below will reveal to you a little known neuropathy curing secret that has travelled over thousands of miles, to not only improving your current nerve pain symptoms, but completely eradicating them…permanently.

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    The 3 step Neuropathy Miracle reversal program.

    Source(s): Reverse Your Neuropathy in 7 Days - http://neuropathy-solution.info
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  • Anonymous
    5 years ago

    Are you sick and tired of the numbness, the prickling, the burning, the intense stabbing pains?

    Looking back, it's absolutely incredible, even delightfully shocking, to see how everything started to come together. Things that I hadn't given any thought to as even pertaining to the neuropathy condition during my years of practice suddenly jumped right out at me - literally from the newspaper - and led me on to further discoveries and well-hidden truths about little-known techniques and approaches that could, when combined in a very particular way, not only control my neuropathy symptoms, but permanently address the condition.

    See more : https://biturl.im/treatneuropathyfast

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  • 1 decade ago

    my mother unfortunatly has neuropathy-she takes neurotin for the tremendous pain she is in.There is no cure for neuropathy and some people have it worse than others.Both my moms parents had diabetes and neuropathy but she is worse off-they all have(had)CHF,PAD.My mom is 52 years old and b/c she has had 5 heart attacks and 3 strokes her heart is working at 20% now.Doctors have said if she has a big heart attack it will take her life b/c she is so weak.Best wishes

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  • 4 years ago

    Doctors Reverse Diabetes Without Drugs - http://Diabetes.neatprim.com

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