Yes, there is a difference. Location Scouts research various local and distant locations to meet the criteria of settings that are in the script. Local locations refer to those areas within a 30 mile jurisdiction of the Motion Picture Association, and anything over that is considered a distant location. Location Scouts now research locations on-line, finding out as many facts as possible before making an actual trip to the location to determine if the speculated area is amenable to the film production. When visiting a proposed location, the Location Scout photographs various buildings and other sites within the speculated area for the Producers to peruse.
Once the film is in development and into production, the Location Manager is responsible for working with all location officials to secure specific buildings and sets for the film, arranging all city, state and town permits required for filming; and generally oversees the activity of all production on the location. The Location Manager works closely with the Unit Manager and the Production Coordinator in regard to hiring of local personnel, arrangement of hotels for cast and crew; etc. Sometimes, Location Managers do the scouting of locations themselves.