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Anonymous asked in 健康其他:保健 · 2 decades ago



3 Answers

  • 2 decades ago
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    Source(s): 自己是SLE
  • Yy
    Lv 7
    2 decades ago

    奎寧 被認為懷孕時服用不引起畸胎 (原文紅色部分)有報導指出奎寧引起畸胎是因一次服用大量 且被用作墮胎劑 (原文藍色部分)母乳奎寧會隨乳汁分泌但一般認為無害Pregnancy    There have been a large number of case reports of    malformations following quinine ingestion in human pregnancy. Many of these pregnancies involved large doses of quinine used as an  abortifacient. The most frequently reported abnormality following  quinine exposure during early pregnancy is hypoplasia of the auditory  nerve with resultant deafness. Other major malformations involving  most organ systems have been reported also. However, the Perinatal   Collaborative Study reported no association between first trimester exposure to quinine and birth defects. In general, there has been no  proven association between quinine at doses used for malarial prophylaxis and an increased risk of malformations.    Third trimester exposure to quinine does not appear to adversely effect uterine contractility. However, an increase in insulin secretion associated with hypoglycaemia has been reported. Therefore, monitoring of blood or serum glucose levels during quinine therapy is   advisable.    Breast milk    Quinine is excreted into breast milk. Following 300 and 640 mg oral doses in six patients, milk concentrations varied up to 2.2 mcg/ml, with an average level of 1 mcg/ml at 3 hours. No adverse effects in   breast fed babies were reported. Quinine is thought to be  compatible with breast feeding (Bennet PN, 1988).

  • Anonymous
    2 decades ago


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