Who would you cast as Manny Pacquiao in a Hollywood movie?

Years from now, a movie will probably be made based on Manny Pacquiao's life and career. If such a Hollywood movie were to be made today, who would you cast as Pacquiao? Who would you cast as his wife, his mother, his trainer, and his ultimate opponent, Floyd Mayweather Jr.?
Update: Interesting cast choices for a hypothetical Manny Pacquiao Hollywood movie here:

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