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Well, you can't sleep because you took it too late, and it is meant to last for an extended period of time. I wouldn't just stop taking it all of a sudden, I would speak to my psychiatrist first. If you are all of a sudden getting bad side effects that you have never experienced before, then maybe you need to lower your dose. A rise in pulse and blood pressure are not unheard of with methylphenidate, so that isn't exactly something to be alarmed about, unless you feel like you are going to have a heart attack or something. Take it with food, make sure you drink enough water, and do not take it later in the day if you miss your dose. Just take it the next day