The medical meaning and drugs pertaining to Epitaxis gave me a nosebleed.
"Systemic Factors:
Drugs - Aspirin, Fexofenadine/Allegra/Telfast, warfarin, ibuprofen, clopidogrel, isotretinoin, desmopressin and others
Alcohol (due to vasodilation)
Allergies
Anemia
Connective tissue disease
Blood dyscrasias
Envenomation by mambas, taipans, kraits, and death adders
Heart failure (due to an increase in venous pressure)
Hematological malignancy
Hypertension
Infectious diseases
Pregnancy
Vascular disorders
Vitamin C or Vitamin K deficiency
von Willebrand's disease"
to be added by Aref: Hard to understand literature, such as this one.
And this one, too.
"Pathophysiology
Nosebleeds are due to the rupture of a blood vessel within the richly perfused nasal mucosa. Rupture may be spontaneous or initiated by trauma. Nosebleeds are reported in up to 60% of the population with peak incidences in those under the age of ten and over the age of 50 and appears to occur in males more than females. An increase in blood pressure (e.g. due to general hypertension) or local blood flow (for example following a cold or infection) will increase the likelihood of a spontaneous nosebleed. Anticoagulant medication and disorders of blood clotting can promote and prolong bleeding. Spontaneous epistaxis is more common in the elderly as the nasal mucosa (lining) becomes dry and thin and blood pressure tends to be higher. The elderly are also more prone to prolonged nose bleeds as their blood vessels are less able to constrict and control the bleeding.
The vast majority of nose bleeds occur in the anterior (front) part of the nose from the nasal septum. This area is richly endowed with blood vessels (Kiesselbach's plexus). This region is also known as Little's area. Bleeding further back in the nose is known as a posterior bleed and is usually due to rupture of the sphenopalatine artery or one of its branches. Posterior bleeds are often prolonged and difficult to control. They can be associated with bleeding from both nostrils and with a greater flow of blood into the mouth."
So, you give me a nosebleed, and I give you one, too!
Merry Christmas and a Happy Nosebleed, everyone!!
Source(s):
The ever lovable Wikipedia.