A concentration gradient is a difference in the concentration of a solute, usually on opposite sides of a membrane.
It is significant because a concentration gradient creates a membrane potential. In accordance with the 2nd law of thermodynamics, the solute would naturally diffuse throughout the solution until the concentration on each side of the membrane is balanced. Because of this, transfer of solute from the high-concentration side of the membrane to the low-concentration side of the membrane can be used to do work.
For example, ATP-synthase, a membrane protein of mitochondria and chloroplasts, uses energy from a membrane potential to convert ADP into ATP— one of the most important processes in all cells.
Life as we know it would not be possible without concentration gradients.
