I have never seen anything that warned against these 3 drugs together. As a matter of fact it is not uncommon to see them prescribed together for Arthritic an Fibro patients. The only warning I could think of would be drousyness. Flexeril is likely to make you drousy on its own but it and tramadol (ultram) would maybe increase the risk.
Your pharmacy would likely have warned you as well, they watch closely for interactions. If you have questions they are also very helpful as far as the dangers of meds and mixing them.
I think you have been misinformed, but you should discuss with pharmacy or a doctor if you have heard differantly just to be sure, you don't just want to take advice of stangers on the net.
Source(s):
Chronic Pain Patient