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scrltsunset scrltsun...
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January 12, 2007
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404 (Level 2)

Resolved Question

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Zoloft and Weight Gain/Loss?

My doctor recently prescribed .25 mg per day of Zoloft for anxiety disorder, panic disorder and OCD. In reading up on the drug online I saw that a significant amount of people complained of weight gain. When calling his office and inquiring about this, he said that as a side effect it wasn't common (the more common is weight loss) and most of peoples complaints were due to an increased appetite and to watch my portions and exercise and it shouldn't be a problem. In reading further consumer reports, I'm not sure I agree with this. I've tried prozac, wellbutrin, and paxil with no help and some with bad side effects. Priorly my doctor prescribed Lexapro but I didn't have it filled so I'm not sure what it would do. Does anyone know if 1) Zoloft will absolutely make a person gain weight, and 2) If there is something else to try that will help treat the above without weight gain, or 3) how to cope with the weight gain so it's not bad or at all? I'm short and don't want to gain 20+ lbs.
  • 3 years ago
SwimnLaur03 by SwimnLau...
Member since:
June 28, 2006
Total points:
1773 (Level 3)

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according to a drug database i have access to as a pharmacy student, > 10% of people on Zoloft experienced anorexia (loss of appetite) as an adverse event, where weight gain and increased appetite were in the 1-10% range. You've probably been seeing weight gain as a side effect all over the internet because who would complain about LOSING weight? not many people! So while more people may be losing weight while on Zoloft, they are not complaining as much as the fewer people who ARE gaining weight. Watching your diet and food intake (as any normal person should do!) will help control your weight, whether it be gaining or losing weight.
  • 3 years ago
Asker's Rating:
4 out of 5
Asker's Comment:
Thanks for the advise and sharing your database info (having real stats is so so much better than scary testimonials)! What you said about people who *would* complain makes good sense. I guess I'll just weight watch and be careful and see how it goes, but not work into a panic over a could-happen.
I have been on Zoloft, Effexor, and Wellbutrin XL. Zoloft and Effexor made me gain weight. I exercised and ate right. The answers are not always in books.

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That's not correct, Zoloft causes short-term weight loss with long-term weight gain. It's actually fairly well documented, I wonder why your 'database' didn't mention it.

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